THE GLUCOCORTICOID RECEPTOR GENE (NR3C1) IS LINKED TO AND ASSOCIATED WITH POLYCYSTIC OVARIAN SYNDROME IN ITALIAN FAMILIES

The glucocorticoid receptor gene (NR3C1) is linked to and associated with polycystic ovarian syndrome in Italian families

Abstract Objectives Components of the hypothalamic-pituitary axis (HPA) pathway are potential mediators of the genetic VEGI SOUP MIX risk of polycystic ovarian syndrome (PCOS).Impaired glucocorticoid receptor (NR3C1) expression and function may underlie impaired HPA-axis cortisol activity, thereby also contributing to the increased adrenal cortisol

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Technical Evaluation Report 50: Optimizing Conferencing Freeware

The increasing range Papaya of options provided by two popular conferencing freeware products, Yahoo Messenger and MSN Messenger, are discussed.Each tool contains features designed primarily for entertainment purposes, which can be customized for use in online education.This report provides suggestions for optimizing the educational potential of th

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ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases

In gut epithelium, IL-22 transmits signals through STAT3 phosphorylation (pSTAT3) which provides intestinal immunity.Many components in the IL-22-pSTAT3 pathway have been identified as risk factors for inflammatory bowel disease (IBD) and some of them are considered as promising therapeutic targets.However, new perspectives are still needed to unde

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